For use only on dogs 23-44 lbs over 8 weeks of age. Contains Fipronil and (S)-methoprene - the active ingredient used in Frontline Plus for dogs. (Fiproguard Plus for dogs is not manufactured by or distributed by Merial. Frontline Plus is a registered trademark of Merial.) Kills: fleas; ticks; chewing lice; flea eggs; flea larvae. Controls flea reinfestation for up to 3 months. Controls mites that may cause sarcoptic mange. Waterproof. Made in USA.